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Feline Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) affects the hepatocytes, which are key parenchemal cells in the liver involved in a variety of cellular functions including carbohydrate, lipid and protein metabolism, detoxification as well as maintenance of liver homeostasis through immune cell activation.

Types of Hepatocellular Carcinoma

Massive HCC

Nodular HCC

Diffuse HCC

Risk Factors

Chronic Liver Disease

Exposure to Toxins

Genetic Predisposition

Age

Signs & Symptoms

Weight Loss

Increased Thirst & Urination

Lethargy

Decreased Appetite

Abdominal Pain/Distention

Ascites

Jaundice

Dyspnea/Rapid Breathing

Chronic Liver Disease

Exposure to Toxins

Genetic Predisposition

Age

Signs & Symptoms

Weight Loss

Increased Thirst & Urination

Lethargy

Decreased Appetite

Abdominal Pain/Distention

Ascites

Jaundice

Dyspnea/Rapid Breathing

Diagnosis

Clinical Exam

Imaging

Blood Tests

Treatment

Surgical Resection

Liver Transplantation

Ablation

Chemotherapy

Available Services for
Characterization

FACS (fluorescence-activated cell sorting)

qPCR (quantitative Polymerase Chain Reaction)

RNAseq (RNA sequencing)

Sterility

HLA (human leukocyte antigen) typing

More on request

Talk to Our Experts

If you are unsure when it comes to selecting the right model and what samples suit your research objectives, you may contact and talk to our experts. We will help you decide and address your concerns.

References

Culp, W.T.N., Drobatz, K.J., Glassman, M.M., Baez, J.L. and Aronson, L.R. (2008), Feline Visceral Hemangiosarcoma. Journal of Veterinary Internal Medicine, 22: 148-152. https://doi.org/10.1111/j.1939-1676.2008.0022.x
 
Johannes, C. M., Henry, C. J., Turnquist, S. E., Hamilton, T. A., Smith, A. N., Chun, R., & Tyler, J. W. (2007). Hemangiosarcoma in cats: 53 cases (1992-2002). Journal of the American Veterinary Medical Association231(12), 1851–1856. https://doi.org/10.2460/javma.231.12.1851
 
McGrath AM, Cook MR, Culp WT, et al. (2022) Hemangiosarcoma of the nasal planum in cats: five cases (2010–2021). Journal of Feline Medicine and Surgery 24(12):e661-e666. doi:10.1177/1098612X221123772
 
Multari, D., Vascellari, M. and Mutinelli, F. (2002), Hemangiosarcoma of the third eyelid in a cat. Veterinary Ophthalmology, 5: 273-276. https://doi.org/10.1046/j.1463-5224.2002.00254.x